Research program
Our research program is divided in three main themes in which complex biological systems are studied using mainly solid- and solution-state NMR:
(1) Studies of membrane systems including the development and characterization of lipid model membranes and their interaction with model systems.








(2) Studies of the molecular structures of natural protein fibers and their use in the development of new biomaterials.








(3) Method development for the studies of structure, molecular organization and interactions of intact unicellular microorganisms (bacteria and microalgae).

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  • Our projects also cover applications related to environmental issues and drug development.
  • Our equipment includes a solids/liquids 600 MHz spectrometer, and a widebore solids 400 MHz spectrometer.

Workflow



Courrier / Mail:
Laboratoire de RMN
Département de Chimie et de Biochimie
Université du Québec à Montréal
Case postale 8888, Succursale Centre-Ville
Montréal, Québec
Canada, H3C 3P8


Paquet / Parcel:

Laboratoire de RMN
Département de Chimie et de Biochimie
Université du Québec à Montréal
2005 rue Jeanne-Mance
Montréal, Québec
Canada, H2X 2J6


Dernières nouvelles
/ Latest news
Derniers articles
/ Latest articles
  • N Ghassemi, A Poulhazan, F Deligey, F Mentink-Vigier, I Marcotte & T Wang* (2022) Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants. Chem. Rev. 122:10036-10086
  • K Kumar, M Sebastiao, AA Arnold, S Bourgault, DE Warschawski* & I Marcotte* (2022) In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes. Biophys. J. 121:1512-1524 (New and Notable: M De Zotti (2022) Bloody spin: I caught you at last. Biophys. J. 121:1352-1353)
  • N Ghassemi, A Poulhazan, F Deligey, F Mentink-Vigier, I Marcotte & T Wang* (2021) Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants. Chem. Rev. in press
  • F Laydevant, M Mahabadi, P Llido, JP Bourgouin, L Caron, AA Arnold, I Marcotte* & DE Warschawski* (2022) Growth-phase dependence of bacterial membrane lipid profile and labeling for in-cell solid-state NMR applications. Biochim. Biophys. Acta. 1864:183819
  • A Poulhazan, MC Dickwella Widanage, A Muszyński, AA Arnold, DE Warschawski, P Azadi, I Marcotte* & T Wang* (2021) Identification and Quantification of Glycans in Whole Cells: Architecture of Microalgal Polysaccharides Described by Solid-State Nuclear Magnetic Resonance. J. Am. Chem. Soc., 143:19374-19388.
  • X Yan, K Kumar, R Miclette Lamarche, H Youssef, GS Shaw, I Marcotte, CE DeWolf, DE Warschawski & E Boisselier (2021) Interactions between the Cell Membrane Repair Protein S100A10 and Phospholipid Monolayers and Bilayers. Langmuir 37:9652–9663
  • PT Nguyen, X Zottig, M Sebastiao, AA Arnold, I Marcotte & S Bourgault (2021) Identification of transmissible proteotoxic oligomer-like fibrils that expand conformational diversity of amyloid assemblies. Comm. Biology 4:939
  • M Millour, JP Gagné, K Doiron, I Marcotte, A Arnold & E Pelletier (2021) Composition of natural organic matter on the aggregative behaviour of silver nanoparticles. Coll. Surf. A. 623:126767
  • Z Bouhlel, AA Arnold, JS Deschênes, JL Mouget, DE Warschawski, R Tremblay & I Marcotte (2021) Investigating the action of the microalgal pigment marennine on Vibrio splendidus by in vivo 2H and 31P solid-state NMR. Biochim. Biophys. Acta Biomembr. 1863:183642
  • DE Warschawski, KV Lakshmi & I Marcotte (2021) Foreword to: Biophysical studies of membrane systems and interactions - Commemorative issue in honour of Professor Michèle Auger Biochim. Biophys. Acta Biomembr. 1863, 183609
Prochaines conférences
/ Next conferences