Research program
Our research program is divided in three main themes in which complex biological systems are studied using mainly solid- and solution-state NMR:
(1) Studies of membrane systems including the development and characterization of lipid model membranes and their interaction with model systems.








(2) Studies of the molecular structures of natural protein fibers and their use in the development of new biomaterials.








(3) Method development for the studies of structure, molecular organization and interactions of intact unicellular microorganisms (bacteria and microalgae).

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  • Our projects also cover applications related to environmental issues and drug development.
  • Our equipment includes a solids/liquids 600 MHz spectrometer, and a widebore solids 400 MHz spectrometer.

Workflow


Courrier / Mail:
Laboratoire de RMN
Département de Chimie et de Biochimie
Université du Québec à Montréal
Case postale 8888, Succursale Centre-Ville
Montréal, Québec
Canada, H3C 3P8


Paquet / Parcel:
Laboratoire de RMN
Département de Chimie et de Biochimie
Université du Québec à Montréal
2005 rue Jeanne-Mance
Montréal, Québec
Canada, H2X 2J6


Dernières nouvelles
/ Latest news
  • Congratulations Dr. Kiran Kumar for your defense, and overall for your Ph. D. and your achievements. Good luck for your post-doc in Florida!
  • The article on slime gets a great coverage in the press.
  • Congratulations to Isabelle Marcotte for her Prix du mérite - Rayonnement of UQAM, this well deserved prize benefits the whole laboratory
  • Congratulations to Mathew Sebastiao for his Ph. D. title!
  • Welcome to Arunima Sandeep who just joined the lab!
  • Congratulations to Kiran Kumar for receiving the Manrao-Rastogi Travel Award to attend the next ICMRBS conference
  • Alexandre Poulhazan defends his thesis. Congratulations Dr. Poul!
  • Alexandre Poulhazan is awarded the Prix du mérite -
    Relève étudiante     of the Science Faculty of UQAM. A well deserved honor!
  • Our article published in Biophys. J. is also picked for the New and Notable section!
Derniers articles
/ Latest articles
  • A. Poulhazan, A. A. Arnold, F. Mentink-Vigier, A. Muszyński, P. Azadi, A. Halim, S. Y. Vakhrushev, H. J. Joshi, T. Wang*, D. E. Warschawski* & I Marcotte* "Molecular-level architecture of Chlamydomonas reinhardtii’s glycoprotein-rich cell wall" Nat. Commun. 15:986 (2024)
  • K. Kumar, A. A. Arnold, R. Gauthier, M. Mamone, J.-F. Paquin, D. E. Warschawski* & I Marcotte* (2024) 19F solid-state NMR approaches to probe antimicrobial peptide interactions with membranes in whole cells. Biochim. Biophys. Acta Biomembr. 1866:184269
  • S. Beauclercq, O. Grenier, A. A. Arnold, D. E. Warschawski, G. H. Wikfors, B. Genard, R. Tremblay & I. Marcotte* (2023) Metabolomics and lipidomics reveal the effects of the toxic dinoflagellate Alexandrium catenella on immune cells of the blue mussel, Mytilus edulis. Harmful Algae 129:102529
  • A Poulhazan, A Baer, G Daliaho, F Mentink-Vigier, AA Arnold, DC Browne, L Hering, S Archer-Hartmann, LE Pepi, P Azadi, S Schmidt, G Mayer, I Marcotte* & MJ Harrington* (2023) Peculiar Phosphonate Modifications of Velvet Worm Slime Revealed by Advanced Nuclear Magnetic Resonance and Mass Spectrometry. J. Am. Chem. Soc., 145:20749-20754.
  • M Sebastiao, M Babych, N Quittot, K Kumar, AA Arnold, I Marcotte & S Bourgault (2023) Development of a novel fluorescence assay for studying lipid bilayer perturbation induced by amyloidogenic peptides using cell plasma membrane vesicles. Biochim. Biophys. Acta. Biomembr. 1865:184118
  • N Ghassemi, A Poulhazan, F Deligey, F Mentink-Vigier, I Marcotte & T Wang* (2022) Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants. Chem. Rev. 122:10036-10086
  • K Kumar, M Sebastiao, AA Arnold, S Bourgault, DE Warschawski* & I Marcotte* (2022) In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes. Biophys. J. 121:1512-1524 (New and Notable: M De Zotti (2022) Bloody spin: I caught you at last. Biophys. J. 121:1352-1353

Prochaines conférences
/ Next conferences